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Big Ideas Reading Group

  • Kepler's Books 1010 El Camino Real Menlo Park, CA, 94025 United States (map)
A Crack in Creation.jpeg

A Crack in Creation by Jennifer Doudna and Sam Sternberg

Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. That is, until 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the gene-editing tool CRISPR--a revolutionary new technology that she helped create--to make heritable changes in human embryos.

The cheapest, simplest, most effective way of manipulating DNA ever known, CRISPR may well give us the cure to HIV, genetic diseases, and some cancers. Yet even the tiniest changes to DNA could have myriad, unforeseeable consequences--to say nothing of the ethical and societal repercussions of intentionally mutating embryos to create "better" humans.


Writing with fellow researcher Sam Sternberg, Doudna shares the thrilling story of her discovery and describes the enormous responsibility that comes with the power to rewrite the code of life.

Earlier Event: November 7
Shannon Messenger